具体折扣请咨询本公司销售人员

Antibody Target: Caspase-3

Alternative Name: CPP32 ,CASP3, apopain, procaspase3,CPP32B,SCA-1,CPP-32,Apopain,Yama

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Immunogen: Synthetic peptide corresponding to the C-terminus of caspase-3 large fragment

Accession#: P42574

Gene ID: 836

Appearance: Colorless liquid

Concentration: 0.2 mg/ml

Formulation: 100 µg (0.2 mg/ml) affinity purified rabbit anti-caspase-3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.

Purification: Affinity purified

Species Reactivity: human, mouse, rat

Application: Western blot

Application & Usage: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects proform and the cleaved large fragment of caspase-3.

Storage Temp.: -20 °C

Shipping: gel pack

Background Descriptions: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-3 is synthesized as an inactive pro-enzyme (32 kDa) that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-3 consists of large (17 kD) and small (12 kD) subunits which associate to form an active enzyme. The active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP and DFF).

Handling: The antibody solution should be gently mixed before use.

• 上一篇：Caspase-3活性检测试剂盒(荧光法)
  下一篇：Caspase-8活性检测试剂盒(荧光法)